Dr. Despina A. Gkika
Hephaestus Laboratory
School of Chemistry-Faculty of Sciences
Democritus University of Thrace
GR 65404 Kavala, Greece
Email: degkika@chem.duth.gr
Dr. Despina A. Gkika
About Me
Dr. Despina A. Gkika is an economist specializing in human-centered, innovative, interdisciplinary systems that promote sustainable interactions between the environment, society, and the economy. She graduated from the Department of Business Economics at the University of Portsmouth in the United Kingdom and received her PhD with a thesis titled "The cost profile of nanomaterials" from the University of Antwerp in Belgium in 2021. She then worked as a postdoctoral researcher in the Department of Chemistry at Democritus University of Thrace. Her research occupies a unique position at the crossroads of economics, chemical technologies, and sustainability science. Her approach includes the economic and sustainability assessment of green/environmental technologies, as well as the interaction between economics, technology, and ecology with applications in green chemistry and the chemical industry. In addition, to address the complex global challenges of sustainable development, its research is applied through the interdisciplinary science of systems, decision-making theory, and economic modeling, with the aim of developing reliable models of human decision-making processes over time and under conditions of uncertainty, in order to understand the determinants of the overall economic value of public goods and services. It incorporates methods from economic valuation and sustainability using techno-economic assessment (TEA), cost-benefit analysis (CBA), dose-response modeling, and life cycle cost (LCC) analysis, strategic frameworks such as the principles of the circular economy and, for financial analysis, activity-based costing (ABC method).
Academic Training and experience
Education
2021
Cost profile of NanomaterialsDoctor of Philosophy (Ph.D.) in Applied Economics
Department of Chemistry
Department of Engineering Management
University of Antwerp, Belgium
Experience
2023 - Present
Research AssistantDemocritus University of Thrace
School of Chemistry, Faculty of Sciences
2022 - 2023
Postdoctoral ResearcherInternational Hellenic University, Greece
School of Chemistry, Faculty of Sciences
2015 - 2021
Scientific researcherInternational Hellenic University
Research
Research Lines
Research Line: Sustainable Engineering and Economics
Combining the principles of Chemical Engineering with economic evaluation, this research direction develops effective and cost-efficient solutions in chemical technologies. Sustainable Engineering and Economics applies scientific and systematic approaches to the rational use and management of material and energy resources, with an emphasis on the design and optimization of materials, production processes, and equipment operation in the chemical and related industries, under conditions of sustainability, safety, environmental protection, and economic viability
Research Line: Circular Economy and Bioeconomy
Pioneering circular and bioeconomic chemical production solutions, this research direction analyzes and evaluates the economic dimension of the transition to circularity. In particular, it examines the costs, benefits, and uncertainties associated with resource recovery, recycling, reuse, and the development of bioeconomic processes in the chemical industry.
Research Line: Accident Prevention and Economic Evaluation
Scientific approaches are applied to safety and protection issues with the aim of optimizing socioeconomic parameters in laboratory chemical processes and the chemical industry.
Research Areas
Research Interests
Resources, water and wastewater resources, environmental economics, water pollution, waste.
Cost-Benefit Analysis & Lifecycle Costing Analysis.
Experimental approaches, choice modeling, cost-benefit analysis.
Research Methods
Solution-oriented research using diverse research methods to address sustainability challenges and problems in their economic context. Bridging innovative economics by techno-economic and sustainability assessment in green chemistry and chemical technology. I use (i) environmental valuation methods, (ii) sustainability assessment methods, iii) strategic planning and financial controlling to production management methods (performance management).
Strategic Performance and Financial Control
- Game theory: supports strategic decision-making in chemical processes, modeling interactions between stakeholders to optimize economic and sustainability outcomes.
- Activity-based costing (ABC): allocates costs to chemical processes and activities, including environmental costs in green chemistry, enabling eco-efficient and economically sustainable management.
Decision and Uncertainty Analysis
- Net present value (NPV): assesses the financial viability of chemical investments.
- Sensitivity analysis: evaluates how changes in inputs affect economic and sustainability outcomes.
- Scenario analysis: explores alternative process or market scenarios to support resilient decision-making.
- Probabilistic analysis/economic risk assessment: quantifies uncertainty in raw materials, production efficiency, and safety events, informing economically sustainable process planning.
Sustainability Performance Indicators
- Economic feasibility
- Cost-benefit analysis (CBA): evaluates the viability of chemical processes and technologies, integrating economic, environmental, and operational impacts.
- Economic profitability
- Techno-economic assessment (TEA): assesses profitability and economic efficiency of chemical technologies, including long-term sustainability considerations.
- Economic sustainability
- Life cycle cost (LCC): calculates total costs over the lifecycle of a process or product, integrating economic and environmental factors.
- Life cycle analysis (LCA): quantifies environmental impacts of chemical processes and their economic implications.
- Sustainability at the macroeconomic level
- Circular economy: evaluates economic and environmental value of resource recovery, recycling, and biobased pathways.
- Atom economy: measures reaction efficiency and waste reduction, linking green chemistry principles with economic sustainability
Funded Projects
Call: Interregional innovation investments strand 2a (HORIZON-I3-2023-INV2a)
Funding agency: European Commission - Horizon Europe
Project title: Interregional tech for forest sustainability
Budget: 7.7M €
Publication Statistics
Citations
1,160+h-index
17Articles
40+Book Chapters
13Research Output
2026
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Pavlos Efthymiopoulos, Ilias Siadimas, D.A. Gkika, Sofia Kavafaki, Ramonna I. Kosheleva, Georgios Maliaris, George Z. Kyzas, 3D printed hierarchical porous amino-functionalized graphene oxide/activated carbon adsorbent composites for pharmaceuticals removal, Chemical Engineering Journal — doi:10.1016/j.cej.2026.172890. -
D.A. Gkika, Dimitra K. Toubanaki, Anna A. Thysiadou, George Z. Kyzas, Athanasia K. Tolkou, Toward Circular and Sustainable Urban Wastewater Treatment, Integrating Adsorption and Advanced Oxidation Processes, Urban Sciences, 2026, 10, 25 — doi:10.3390/urbansci10010025. -
D.A. Gkika, George Z. Kyzas, Reusability of Spent Adsorbents for a Circular Materials Economy in a Chemical and Sustainable Industry, RSC Sustainability, 2026 — doi:10.1039/D5SU00802F.
2025
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D.A. Gkika, A.K. Tolkou, G.Z. Kyzas, Comparison of nanocomposites groups performance in cements, Earth: Environmental Sustainability 1 (2025) 176–194 — doi:10.53941/eesus.2025.100014. -
D.A. Gkika, G.Z. Kyzas, Cost evidence yields the viability of metal oxides synthesis routes, ACS Sustainable Chemistry & Engineering 13 (2025) 17370–17379 — doi:10.1021/acssuschemeng.5c06752. -
D.A. Gkika, N. Vordos, A.C. Mitropoulos, G.Z. Kyzas, Economic evaluation during physicochemical characterization process: A cost-benefit Analysis, ChemEngineering 9 (2025) Article 95 — doi:10.3390/chemengineering9050095. -
D.A. Gkika, K. N. Maroulas, G.Z. Kyzas, Various Reduced Graphene Oxide Green Synthetic Routes: Comparing the Cost Procedures, ACS Omega, Aug. 2025 — doi:10.1021/acsomega.5c04090. -
D.A. Gkika, Athanasia K. Tolkou, Stavros G. Poulopoulos, Ioannis K. Kalavrouziotis, George Z. Kyzas, Cost-effectiveness of regenerated green materials for removal of pharmaceuticals from wastewater, Waste Management, Volume 204, 2025 — doi:10.1016/j.wasman.2025.114952. -
D.A. Gkika, A.K. Tolkou, I.A. Katsoyiannis, G.Z. Kyzas, The adsorption-desorption-regeneration pathway to a circular economy, Separation and Purification Technology 368 (2025) 132996 — doi:10.1016/j.seppur.2025.132996.
2024
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A. Vlachou, D.A. Gkika, P. Efthymiopoulos, G.Z. Kyzas, A. Tsoupras, Copper- and iron-based nanoflowers in cancer theranostics, Applied Sciences 14 (2024) 11294 — doi:10.3390/app142311294. -
D.A. Gkika, A.C. Mitropoulos, G.Z. Kyzas, How economic theories shape chemical technologies profile, ChemEngineering 8 (2024) Article 91 — doi:10.3390/chemengineering8050091. -
D.A. Gkika, M. Chalaris, G.Z. Kyzas, Review of methods for obtaining rare earth elements from recycling and their impact on the environment and human health, Processes 12 (2024) Article 1235 — doi:10.3390/pr12061235. -
A. Tsoupras, D.A. Gkika, I. Siadimas, I. Christodoulopoulos, P. Efthymiopoulos, G.Z. Kyzas, The multifaceted effects of non-steroidal and non-opioid anti-inflammatory and analgesic drugs on platelets: Current knowledge, limitations and future perspectives, Pharmaceuticals 17 (2024) 627 — doi:10.3390/ph17050627. -
Eduardo Alberto López-Maldonado, Nadeem A Khan, ... , D.A. Gkika, George Z. Kyzas, Magnetic polymeric composites: discover their potential for separating and degrading micro/nano plastics, Desalination and Water Treatment — doi:10.1016/j.dwt.2024.100198. -
D.A. Gkika, A.K. Tolkou, D.A. Lambropoulou, D.N. Bikiaris, P. Kokkinos, I.K. Kalavrouziotis, G.Z. Kyzas, Application of Molecularly Imprinted Polymers (MIPs) as environmental separation tools, RSC Applied Polymers, 2024 — doi:10.1039/D3LP00082F. -
D.A. Gkika, K. Ladomenou, M. Bououdina, A.C. Mitropoulos, G.Z. Kyzas, Adsorption and photocatalytic applications of porphyrin-based materials for environmental separation processes: A review, Science of the Total Environment 908 (2024) 168293 — doi:10.1016/j.scitotenv.2023.168293. -
N. Mittas, D.A. Gkika, K. Georgiou, ... , G.Z. Kyzas, Bibliometric research analysis of Molecularly Imprinted Polymers (MIPs) for environmental applications, Environmental Science and Pollution Research, 2024 — doi:10.1007/s11356-023-29235-9.
2023
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M. Chalaris, D.A. Gkika, A.K. Tolkou, G.Z. Kyzas, Advancements and sustainable strategies for treatment and management of metallurgical wastewater, Environmental Science and Pollution Research, 2023, 30, 119627–119653 — doi:10.1007/s11356-023-30891-0. -
A. Theodoropoulou, D.A. Gkika, A. Alodhayb, G.Z. Kyzas, A critical evaluation of the safety datasheets of graphene materials, Journal of Nanoparticle Research 25 (2023) 99 — doi:10.1007/s11051-023-05753-y. -
D.A. Gkika, A.K. Tolkou, E. Evgenidou, D.N. Bikiaris, D.A. Lambropoulou, A.C. Mitropoulos, I.K. Kalavrouziotis, G.Z. Kyzas, Fate and removal of microplastics from industrial wastewaters, Sustainability 15 (2023) 6969 — doi:10.3390/su15086969. -
D.A. Gkika, A.C. Mitropoulos, P. Kokkinos, D.A. Lambropoulou, I.K. Kalavrouziotis, D.N. Bikiaris, G.Z. Kyzas, Modified chitosan adsorbents in pharmaceutical simulated wastewaters: A review, Carbohydrate Polymer Technologies and Applications 5 (2023) 100313 — doi:10.1016/j.carpta.2023.100313. -
D.A. Gkika, V. Karmali, D.A. Lambropoulou, A.C. Mitropoulos, G.Z. Kyzas, Membranes coated with graphene-based materials: A review, Membranes 13 (2023) 127 — doi:10.3390/membranes13020127. -
D.A. Gkika, Georgios Maliaris, Nick Vordos, Athanasios C. Mitropoulos, George Z. Kyzas, Cost Profile of 3D Printing Using Biomaterials on a Lab Scale, Biointerface Research in Applied Chemistry, 2023 — doi:10.33263/BRIAC131.093.
2022
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D.A. Gkika, V. Filiz, S. Rangou, G.Z. Kyzas, A.C. Mitropoulos, Cost Profile of Membranes That Use Polymers of Intrinsic Microporosity (PIMs), Membranes 2022 — doi:10.3390/membranes12040433. -
D.A. Gkika, A.C. Mitropoulos, D.A. Lambropoulou, I.K. Kalavrouziotis, G.Z. Kyzas, Cosmetic wastewater treatment technologies: a review, Environmental Science and Pollution Research, 2022 — doi:10.1007/s11356-022-23045-1. -
D.A. Gkika, A.C. Mitropoulos, G.Z. Kyzas, Why reuse spent adsorbents? The latest challenges and limitations, Science of the Total Environment, 2022 — doi:10.1016/j.scitotenv.2022.153612.
2015-2021
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E.V. Liakos, D.A. Gkika, A.C. Mitropoulos, K.A. Matis, G.Z. Kyzas, On the combination of modern sorbents with cost analysis: A review, Journal of Molecular Structure 1229 (2021) 129841 — doi:10.1016/j.molstruc.2020.129841. -
D.A. Gkika, N. Vordos, L. Magafas, A.C. Mitropoulos, G.Z. Kyzas, Risk return profile of nanomaterials, Journal of Molecular Structure 1228 (2021) 129740 — doi:10.1016/j.molstruc.2020.129740. -
D.A. Gkika, N. Vordos, M. Maragakis, K.E. Tilkeridis, L. Magafas, A.C. Mitropoulos, G.Z. Kyzas, Patents of nanomaterials related with cancer treatment applications, Journal of Nanoparticle Research 22 (2020) 335 — doi:10.1007/s11051-020-05052-w. -
N. Vordos, D.A. Gkika, G. Maliaris, K.E. Tilkeridis, ..., How 3D Printing and Social Media Tackles the PPE Shortage during Covid–19 Pandemic, Safety Science, 2020 — doi:10.1016/j.ssci.2020.104870. -
N. Vordos, D.A. Gkika, D.V. Bandekas, Wheatstone Bridge and Bioengineering, Journal of Engineering Science and Technology Review, 2020 — doi:10.25103/jestr.135.02. -
D.A. Gkika, E.V. Liakos, N. Vordos, C. Kontogoulidou, L. Magafas, D.N. Bikiaris, A.C. Mitropoulos, G.Z. Kyzas, Cost Estimation of Polymeric Adsorbents, Polymers 11(5), 925, May 2019 — doi:10.3390/polym11050925. -
D.A. Gkika, K. Ovaliadis, N. Vordos, L. Magafas, Managing complexity: the case of nanomaterials, J. Nanoparticle Res., 21(1), 17, Jan. 2019 — doi:10.1007/s11051-018-4456-3. -
D.A. Gkika, L. Magafas, P. Cool, J. Braet, Balancing nanotoxicity and returns in health applications: The Prisoner’s Dilemma, Toxicology Journal 393 (2018) 83–89 — doi:10.1016/j.tox.2017.11.008. -
D.A. Gkika, N. Vordos, J.W. Nolan, A.C. Mitropoulos, E.F. Vansant, P. Cool, J. Braet, Price tag in Nanomaterials?, Journal of Nanoparticle Research, accepted April 2017 — doi:10.1007/s11051-017-3875-x. -
N. Vordos, S. Giannakopoulos, D.A. Gkika, J.W. Nolan, Ch. Kalaitzis, D.V. Bandekas, C. Kontogoulidou, A.Ch. Mitropoulos, S. Touloupidis, Kidney Stone Nano-Structure – Is there an Opportunity for Nanomedicine Development?, Biochimica et Biophysica Acta (BBA) - General Subjects, 2017 — doi:10.1016/j.bbagen.2017.01.026. -
D.A. Gkika, J.W. Nolan, E.F. Vansant, A.C. Mitropoulos, P. Cool, J. Braet, C. Kontogoulidou, A framework for health-related nanomaterial grouping, Biochimica et Biophysica Acta, 2016 — doi:10.1016/j.bbagen.2016.08.014. -
D.A. Gkika, C. Kontogoulidou, J.W. Nolan, E.F. Vansant, A.C. Mitropoulos, P. Cool, J. Braet, Nano-patents and literature frequency as Statistical Innovation Indicator for the use of nano-porous material, Journal of Engineering Science and Technology Review, 2016 — doi:10.25103/jestr.095.03. -
G.A. Papakostas, J.W. Nolan, N. Vordos, D.A. Gkika, M.E. Kainourgiakis, A.C. Mitropoulos, On 3D Reconstruction of Porous Media by Using Spatial Correlation Functions, Journal of Engineering Science and Technology Review 8(4), 78–83, 2015 — doi:10.25103/jestr.084.12. -
J.W. Nolan, D.A. Gkika, N. Vordos, I.K. Kazanidis, A.Ch. Mitropoulos, On the Archiving and Visualisation of Scientific Data, Journal of Engineering Science and Technology Review 8(4), 40–43, 2015 — doi:10.25103/jestr.084.06.
Network
Research Collaborations with Academic Institutions and Research Institutes Abroad
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Prince Sultan University, Riyadh, Saudi Arabia
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Imam Mohammad Ibn Saud Islamic University, Saudi Arabia
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King Khalid University, Saudi Arabia
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Universiteit Antwerpen, Belgium
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Helmholtz-Zentrum Hereon GmbH, Germany
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Xinjiang Technical Institute of Physics and Chemistry, China
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Universidad Complutense de Madrid, Spain
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Universidad Autónoma de Baja California, Mexico
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Tecnológico de Monterrey, Mexico
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Adama Science and Technology University, Ethiopia
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Nazarbayev University, Kazakhstan
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University of Karachi, Pakistan
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Indian Institute of Science, India
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Mewat Engineering College, India
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Hitit University, Turkey
Research Collaborations with Academic Institutions and Research Institutes in Greece
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Aristotle University of Thessaloniki
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Technical University of Crete
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University of Piraeus
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Hellenic Open University
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National Center for Scientific Research “Demokritos”
Teaching
Postgraduate Courses

Research Methods
MSc In Cosmetic ChemistrySchool of Chemistry
Democritus University of Thrace
Kavala, Greece
Contact
Hephaestus Laboratory
School of Chemistry - Faculty of Sciences
Democritus University of Thrace
GR 65404 Kavala, Greece